An interesting example of the persistence of site has recently been published in the British Medical Journal. @DouglasNobleMD has found a remarkable similarity between two maps produced 120 years apart.
1. Here is a modern map showing the occurrence of diabetes in parts of East London.
2. And here is Booth's 1889 analysis of poverty in exactly the same streets.
Even though the symptoms and immediate causes are different (diabetes and junk food versus malnutrition), the root causes of poverty remain in exactly the same locations.
Douglas Noble et al, Feasibility study of geospatial mapping of chronic disease risk to inform public health commissioning. BMJ Open 2012;2:e000711 doi:10.1136/bmjopen-2011-000711
Via Daily Mail, 17 February 2012